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Mary Frances McMullin Selected Research

Polycythemia (Erythrocytosis)

5/2024Erythrocytosis: Diagnosis and investigation.
1/2021Genetic Background of Congenital Erythrocytosis.
1/2018Absence of CALR Mutations in Idiopathic Erythrocytosis Patients with Low Serum Erythropoietin Levels.
11/2016Gene panel sequencing improves the diagnostic work-up of patients with idiopathic erythrocytosis and identifies new mutations.
2/2016LNK mutations and myeloproliferative disorders.
1/2014The role of PHD2 mutations in the pathogenesis of erythrocytosis.
12/2012Diagnosis and management of congenital and idiopathic erythrocytosis.
2/2010HIF pathway mutations and erythrocytosis.
9/2009Identification of high oxygen affinity hemoglobin variants in the investigation of patients with erythrocytosis.
4/2009Erythrocytosis-associated HIF-2alpha mutations demonstrate a critical role for residues C-terminal to the hydroxylacceptor proline.
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Mary Frances McMullin Research Topics

Disease

22Polycythemia (Erythrocytosis)
05/2024 - 09/2003
17Neoplasms (Cancer)
11/2023 - 04/2009
13Primary Myelofibrosis (Myelosclerosis)
02/2024 - 09/2005
9Hypoxia (Hypoxemia)
11/2023 - 09/2003
8Polycythemia Vera
01/2023 - 02/2007
6Anemia
02/2024 - 01/2006
5Thrombosis (Thrombus)
01/2023 - 03/2011
5Essential Thrombocythemia
12/2022 - 02/2007
5primary familial and congenital Polycythemia
01/2021 - 01/2006
4Hemorrhage
01/2023 - 10/2017
4Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2023 - 08/2013
4Leukemia
01/2019 - 08/2006
2Thrombocytopenia (Thrombopenia)
11/2022 - 10/2017
2Congenital Abnormalities (Deformity)
01/2021 - 12/2012
2Thrombocytosis (Thrombocythemia)
12/2019 - 12/2018
2Splenomegaly
01/2018 - 01/2015
2Hyperplasia
05/2009 - 12/2007
2Myeloproliferative Disorders (Myeloproliferative Disorder)
06/2007 - 09/2005
1Fatigue
11/2023
1Multiple Myeloma
03/2023
1Carcinogenesis
03/2023
1Cardiovascular Diseases (Cardiovascular Disease)
11/2022
1Second Primary Neoplasms (Neoplasms, Second)
01/2020
1Skin Neoplasms (Skin Cancer)
01/2019
1Inflammation (Inflammations)
12/2018
1Ischemia
12/2018
1Hypertension (High Blood Pressure)
12/2018
1Embolism (Embolus)
12/2018
1Varicose Veins (Varicose Vein)
01/2018
1Cytopenia
01/2018
1Ascites
01/2018
1Alopecia (Baldness)
10/2015
1Neoplasm Metastasis (Metastasis)
08/2015
1Breast Neoplasms (Breast Cancer)
08/2015
1Pharyngitis (Sore Throat)
02/2014
1Pneumonia (Pneumonitis)
02/2014
1Respiratory Tract Infections (Respiratory Tract Infection)
02/2014
1Sinusitis
02/2014
1Human Influenza (Influenza)
02/2014
1Infections
02/2014
1Cystitis
02/2014
1Bronchitis
02/2014

Drug/Important Bio-Agent (IBA)

15ErythropoietinFDA Link
05/2024 - 09/2003
12Oxygen (Dioxygen)IBA
01/2021 - 09/2003
8Hemoglobins (Hemoglobin)IBA
01/2021 - 01/2009
7ruxolitinibIBA
02/2024 - 01/2015
5Prolyl Hydroxylases (Prolyl Hydroxylase)IBA
11/2023 - 01/2006
5Proteins (Proteins, Gene)FDA Link
08/2015 - 05/2006
4Janus KinasesIBA
11/2023 - 09/2005
4Transcription Factors (Transcription Factor)IBA
01/2014 - 01/2006
3N- (cyanomethyl)- 4- (2- ((4- (4- morpholinyl)phenyl)amino)- 4- pyrimidinyl)benzamideIBA
02/2024 - 11/2023
3Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2021 - 12/2012
3CytokinesIBA
12/2019 - 06/2007
3EnzymesIBA
01/2014 - 01/2006
3Phenylalanine (L-Phenylalanine)FDA Link
06/2007 - 09/2005
3Valine (L-Valine)FDA Link
06/2007 - 09/2005
2Janus Kinase InhibitorsIBA
02/2024 - 11/2014
2Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
11/2023 - 09/2021
2CalreticulinIBA
04/2023 - 10/2016
2Hydroxyurea (Hydrea)FDA LinkGeneric
12/2022 - 01/2020
2givinostatIBA
01/2021 - 01/2020
2VorinostatFDA Link
11/2017 - 07/2014
2IronIBA
01/2014 - 10/2007
2endothelial PAS domain-containing protein 1IBA
06/2008 - 10/2007
1Biomarkers (Surrogate Marker)IBA
02/2024
1Cytarabine (Cytosar-U)FDA LinkGeneric
11/2023
1activin AIBA
11/2023
1Danazol (Azol)FDA LinkGeneric
11/2023
1Proteasome InhibitorsIBA
03/2023
1Gemtuzumab (Mylotarg)FDA Link
01/2023
1InterferonsIBA
12/2022
111- (2- pyrrolidin- 1- ylethoxy)- 14,19- dioxa- 5,7,26- triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa- 1(25),2(26),3,5,8,10,12(27),16,21,23- decaeneIBA
11/2022
1Rituximab (Mabthera)FDA Link
04/2022
1Monoclonal AntibodiesIBA
04/2022
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
09/2021
1Erythropoietin Receptors (Erythropoietin Receptor)IBA
01/2021
1Janus Kinase 2IBA
01/2021
1pomalidomideIBA
01/2021
1Histones (Histone)IBA
09/2020
1RNA (Ribonucleic Acid)IBA
09/2020
14,5,6,7- tetrahydroisoxazolo(4,5- c)pyridin- 3- ol (THPO)IBA
12/2019
1Drug CombinationsIBA
01/2019
1Pipobroman (Vercyte)FDA Link
01/2019
1DNA (Deoxyribonucleic Acid)IBA
01/2018
1Azacitidine (5 Azacytidine)FDA Link
11/2017
1Mutant Proteins (Protein, Mutant)IBA
02/2016
1Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric
10/2015
1Arsenic Trioxide (Trisenox)FDA Link
10/2015
1Alanine Transaminase (SGPT)IBA
10/2015
1OsteopontinIBA
08/2015
1Cadherins (E-Cadherin)IBA
08/2015
1Transforming Growth Factor beta (TGF-beta)IBA
08/2015
1HematinicsIBA
01/2015
1Vascular Endothelial Growth FactorsIBA
07/2014
1Histone Deacetylase InhibitorsIBA
07/2014
1ORALIT (ORS)IBA
02/2014

Therapy/Procedure

14Therapeutics
02/2024 - 04/2009
3Drug Therapy (Chemotherapy)
11/2023 - 08/2013
1Liver Transplantation
01/2018
1Aftercare (After-Treatment)
07/2014